(R)-3,3-Diethyl-1-(2-hydroxy-1-phenylethyl)piperidin-2-one
نویسندگان
چکیده
منابع مشابه
Crystal structure of (-)-(1'R)-1-(2'-hydroxy-1'-phenyl-ethyl)-1H-pyridin-2-one.
wide interest because the 1H-pyridin-2-ones obtained in this process are versatile synthetic building blocks in the synthesis of alkaloids.1–5 The title compound, (–)-(1′R)-1-(2′-hydroxy-1′-phenyl-ethyl)1H-pyridin-2-one II, was prepared by stirring a solution of pyridinium salt, I (4.0 mmol), in water (25 ml) and cooled to 5 ̊C (Scheme 1). A solution of K3Fe(CN)6 (11 eq.) in water (30 ml) was ad...
متن کامل(R)-3,3-Diethyl-1-(2-hydroxy-1-phenylethyl)piperidin-2-one
In the title compound C(17)H(25)NO(2), the piperidin-2-one ring adopts an envelope conformation with the C atom in the 5-position as the flap. The crystal packing is stabilized by inter-molecular O-H⋯O hydrogen bonds, building a infinite chain along the b-axis direction. C-H⋯π inter-actions further stabilize the crystal packing.
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متن کامل(E)-3-(2,3-Dimethoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one
The mol-ecular conformation of the title compound, C(18)H(18)O(5), is stabilized by a strong intra-molecular hydrogen bond between the hydroxyl and carbonyl groups. The C=C double bond displays an E configuration while the carbonyl group shows an S-cis configuration relative to the double bond. The dihedral angle between the two rings is 15.0 (1)°.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2012
ISSN: 1600-5368
DOI: 10.1107/s1600536812025433